Abstract
Ultraviolet (UV) exposure induces photodamage of skin. It is a matter of concern that the level of UV radiation reaching the earth surface is increasing as a result of depletion of the stratospheric ozone, and climate change. It is urgently necessary to develop strategies to protect the skin from UV-induced injuries. Tea extracts are gaining increasing attention as asupplement in skin care products. However, the factors contributing to the photoprotective effects of tea extracts have not been systematically defined and conflicting results about the effect of tea extracts on photodamage have been reported. In this paper, the literature dealingwith the use of tea and its extracts for the prevention of photodamage to the skin as well as the photoprotective effects of tea and its extracts have been highlighted. The potential chemopreventive agents in tea include catechins, caffeine, polysaccharides, apigenin and luteolin which inhibit, reverse or retard the process of the skin photodamage via their sunscreen and antioxidant properties, regulation of signal transduction pathway and gene expression, alleviation of DNA damage, and modulation immunological function are also presented. Existing gaps in this research field include incomplete clarity of photochemopreventive mechanism of tea, the adverse or side effects of tea extracts owing to residues or impurity and the instability of the functional components of tea during storage.Keywords: Camellia sinensis; Photoageing, Antioxidant, Tea extracts, Sunburn, DNA damage; Immunological modulation; Gene expression.
Highlights
The solar ultraviolet (UV) radiation reaching the earth’s surface is increasing because of depletion of the ozone layer
Laboratory tests showed that oral feeding or topical application of green tea polyphenols (GTPs) afforded protection against UVB induced immunosuppression and cutaneous inflammatory responses in C3H mice
Topical application of epigallocatechin gallate (EGCG) before UVB exposure reduced the number of CD11b +monocytes/macrophages and neutrophils infiltrating into skin inflammatory lesions, which are considered to be responsible for creating the UV-induced immunosuppressive state
Summary
The solar ultraviolet (UV) radiation reaching the earth’s surface is increasing because of depletion of the ozone layer. The skin sunburn attenuating effect of GTE is considered to be related to its activities of antioxidation, inhibiting the decrease of dermal collagen and preventing from DNA damage. EGCG treatment significantly reduced UVBinduced erythema and UVA-induced skin damage (roughness and sagginess) by inhibiting the decrease of dermal collagen in hairless mouse skin.
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