Abstract
Objective: Photodynamic therapy (PDT) is an alternative treatment for a variety of malignancies. Application of PDT in the treatment of gynecologic malignancies has been limited, however preliminary results are promising. PDT involves administering a systemic injection of Photofrin II, a selective tumor photosensitizer hematoporphyrin derivative, followed by exposure of tumor tissue to visible light at 630nm. The photodynamic destruction of tumor exhibits both cytocidal and vascular effects that may contribute to the tumorcidal effects observed.
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