Abstract
BackgroundFor practical straight-line scanning in photoacoustic imaging (PAI), serious artifacts caused by missing data will occur. Traditional total variation (TV)-based algorithms fail to obtain satisfactory results, with an over-smoothed and blurred geometric structure. Therefore, it is important to develop a new algorithm to improve the quality of practical straight-line reconstructed images.MethodsIn this paper, a combined nonlocal patch and TV-based regularization model for PAI reconstruction is proposed to solve these problems. A modified adaptive nonlocal weight function is adopted to provide more reliable estimations for the similarities between patches. Similar patches are searched for throughout the entire image; thus, this model realizes adaptive search for the neighborhood of the patch. The optimization problem is simplified to a common iterative PAI reconstruction problem.Results and conclusionThe proposed algorithm is validated by a series of numerical simulations and an in vitro experiment for straight-line scanning. The results of patch-TV are compared to those of two mainstream TV-based algorithms as well as the iterative algorithm only with patch-based regularization. Moreover, the peak signal-to-noise ratio, the noise robustness, and the convergence and calculation speeds are compared and discussed. The results show that the proposed patch-TV yields significant improvement over the other three algorithms qualitatively and quantitatively. These simulations and experiment indicate that the patch-TV algorithm successfully solves the problems of PAI reconstruction and is highly effective in practical PAI applications.
Highlights
For practical straight-line scanning in photoacoustic imaging (PAI), serious artifacts caused by missing data will occur
In this paper, nonlocal patch regularization is incorporated into the total variation (TV)-based photoacoustic imaging reconstruction model to effectively improve the performance in practical limited-view scanning
The similar patches for weighted calculation for a certain patch Pxi are searched in the entire image according to the value of the weight function W(xi, xj)
Summary
A combined nonlocal patch and TV-based regularization model for PAI reconstruction is proposed to solve these problems. A modified adaptive nonlocal weight function is adopted to provide more reliable estimations for the similarities between patches. Similar patches are searched for throughout the entire image; this model realizes adaptive search for the neighborhood of the patch. The optimization problem is simplified to a common iterative PAI reconstruction problem
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