Abstract
Photoacoustic (PA) imaging is an emerging imaging technology with potential for preclinical biomedical research and clinical applications. PA imaging, which relies on the generation of broadband acoustic waves via the absorption of intensity-modulated light in tissue, offers the combination of strong optical contrast and high spatial resolution provided by ultrasound. For excitation wavelengths in the visible and near-infrared region, image contrast is predominately due to haemoglobin. Exogenous contrast agents, such as dyes or genetically expressed absorbers, can be used to obtain targeted molecular contrast. Over the past decade, PA imaging has rapidly evolved into different microscopy and tomography modalities, while novel methodologies have led to a variety of exciting applications. This chapter explains the basic principles of PA imaging, its implementation in the different modalities and provides examples of applications to morphological, functional and molecular imaging. Furthermore, the challenge of recovering quantitative information from PA image data sets is described.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.