Abstract
In this work we demonstrate a photoacoustic system which can identify the deformation of blood vessels under external pressure. Using photoacoustic imaging method, the vessel internal diameter can be derived from the peak-to-peak time interval of the laser (532nm) induced the photoacoustic signals. Comparisons with the actual vessel inter diameter show that the relative deviation is less than 4%, which proves the validity of this method. Interestingly, we find that the axial diameter of the blood vessel and the blood volume increase monotonously with increasing transient pressure, and the laser-induced photoacoustic signal is mainly contributed by the blood inside the vessel. Our results suggest a new way for continuous monitoring of the deformation of blood vessels under pressure.
Highlights
Arterial blood pressure provides a basis for clinical diagnosis, treatment and perioperative nursing, is an important parameter for the diagnosis and prevention of cardiovascular disease
We find that the axial diameter of the blood vessel and the blood volume increase monotonously with increasing transient pressure, and the laser-induced photoacoustic signal is mainly contributed by the blood inside the vessel
We found that the diameter change of vessel under different pressures can be obtained by using photoacoustic imaging technology
Summary
Arterial blood pressure provides a basis for clinical diagnosis, treatment and perioperative nursing, is an important parameter for the diagnosis and prevention of cardiovascular disease. The direct measurement is performed by puncturing the artery through a cutaneous catheter and using a pressure sensor to obtain the blood pressure. This method is highly accurate and is recognized as international standard.. The indirect measurement is performed by measuring the pulsation of arterial wall and the change of blood vessel volume to obtain the blood pressure. This noninvasive method has the advantages of high continuity, low infection rate, and high safety, is possible for in-house daily use. It is highly desired to design a simple, fast, convenient and comfortable continuous method for the blood pressure measurement
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