Phosphonacetyl-L-aspartate: An aspartate transcarbamylase inhibitor causing larval death and rudimentary wing phenocopies in Drosophila melanogaster

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Phosphonacetyl-L-aspartate, an inhibitor and transition state analogue of aspartate transcarbamylase, has been found to cause rudimentary wing phenocopies and larval death in Drosophila melanogaster. We believe this compound may prove useful as a selection agent for regulatory mutations at the rudimentary locus.