Abstract
Aortae of female rats 3 and 7 months of age were examined for phospholipid content and the activity of different phospholipases. The data were compared to those obtained from male rats and female rats ovariectomized at the age of 3–4 weeks. The aortae of female rats had a lower concentration of phosphatidyl ethanolamine and of lecithin, than those of male rats. Ovariectomy resulted in a rise in phospholipid concentration, which was lowered to some extent, by treatment with estrogen. The phosphatide acyl-hydrolase (EC 3.1.1.4) activity towards phosphatidyl ethanolamine of 3-month-old female aortae was significantly higher than of male aortae. In aortae of 7-month-old rats the phosphatide acyl-hydrolase activity towards both lecithin and phosphatidyl ethanolamine was higher in female than in male or ovariectomized rats. A possible correlation between the difference in phosphatide acyl-hydrolase and 5'-nucleotidase activities of male and female aortae has been discussed with respect of hormonal control of aortic enzymes.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
