Abstract

Reaction time is accelerated if a loud (startling) sound accompanies the cue—the “StartReact” effect. Animal studies revealed a reticulospinal substrate for the startle reflex; StartReact may similarly involve the reticulospinal...

Highlights

  • Stevens-J­ohnson syndrome (SJS) is a hypersensitivity reaction with a distinctive clinical pattern characterised by targetoid skin lesions and lesions of at least two anatomic mucosal membranes sites

  • A 23-­year-o­ ld Caucasian female patient was admitted to our hospital due to oral and genital erosions accompanied by erythematous macules with central dusky violaceous region on her thorax, face, lower extremities, palms and soles

  • The patient was tested for influenza A virus, adenovirus and rotavirus, all of which were negative, indicating that there were no additional infections at the time of the SARS-C­ oV-2 infection

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Summary

Introduction

Stevens-J­ohnson syndrome (SJS) is a hypersensitivity reaction with a distinctive clinical pattern characterised by targetoid skin lesions and lesions of at least two anatomic mucosal membranes sites. Most patients show evidence of SJS 7 to 21 days after the first drug exposure.[1] Viral infections such as COVID-19 might induce SJS.[2 3] Drug eruptions are often clinically indistinguishable from viral infections.[4] Johnson syndrome in a patient with COVID-19.

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