Abstract
Salmonellaenterica is responsible for alimentary toxic infections associated with the consumption of contaminated poultry products and the antimicrobial resistant patterns of Salmonella circulating in the Tolima region are currently unknown. To address this issue, both the phenotype and genotype antibiotic resistance patterns of 47 Salmonella isolated from raw chicken carcasses sold at the Ibague city were analyzed by the disc diffusion, microdilution and PCR assays. All 47 Salmonella isolates showed resistance to five or more antimicrobial agents. Resistance to Ampicillin (AMP), Amikacin (AMK), Gentamicin (GEN), Tobramycin (TOB), Cefazoline (CFZ), Cefoxitin (FOX), Nitrofurantoin (NIT), Trimethoprim-Sulfamethoxazole (SXT), Tetracycline (TET), Ciprofloxacin (CIP) and Enrofloxacin (ENR) was observed in 42.35% of Salmonella isolates. All tested S. Paratyphi B var Java isolates showed resistance to at least 12 antibiotics. S. Hvittingfoss showed resistance to 5 antibiotics, whereas S. Muenster showed resistance to seven antibiotics. Amplification of a number of antibiotic resistance genes showed that blaTEM (100%) correlated well with resistance to Ampicilin and Cephalosporin, whereas aadB (87%) correlated well with resistance to Aminoglycosides. It is concluded that Salmonella isolated from raw chicken meat marketed at Ibague showed MDR by both phenotypic and genotypic methods and they may represent an important threat to human health. Additional studies are needed to establish the relationship between antibiotic resistance in Salmonella from poultry products and clinical isolates.
Highlights
Salmonella enterica is a large group of Gram-negative bacteria that cause an infectious disease called salmonellosis
All 47 Salmonella isolates (100%) were resistant to five antibiotics belonging to Aminoglycosides (AMK, GEN, TOB) and Cephalosporin (FOX and CFZ) classes (Table 1)
At least 42.35% (20/47) of Salmonella isolates were found to be multiple drug resistance (MDR) strains that showed resistance to eleven (AMP, AMK, GEN, TOB, CFZ, FOX, NIT, SXT, TET, CIP and ENR) or more antibiotics belonging to seven antibiotic classes (Aminoglycosides, Penicillin, Cephalosporin, Nitrofurans, Sulfonamides/Trimethoprim, Tetracycline and quinolones)
Summary
Salmonella enterica is a large group of Gram-negative bacteria that cause an infectious disease called salmonellosis. At least 42.35% (20/47) of Salmonella isolates were found to be MDR strains that showed resistance to eleven (AMP, AMK, GEN, TOB, CFZ, FOX, NIT, SXT, TET, CIP and ENR) or more antibiotics belonging to seven antibiotic classes (Aminoglycosides, Penicillin, Cephalosporin, Nitrofurans, Sulfonamides/Trimethoprim, Tetracycline and quinolones).
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