Abstract

ABSTRACT Mycotoxins, which are produced by some fungi under improper storage conditions before or after harvesting in plant products, cause acute or chronic toxicities. Ochratoxin A (OA) which is also one of the harmful mycotoxins pose a threat to animal and human health. This study was carried out in order to determine OA levels in mixed feed and feedstuffs materials used in livestock enterprises throughout Sivas province. The 59 mixed feeds and 30 feedstuffs materials collected from different enterprises was analysed. Ochratoxin A concentrations were quantified using immunoassay (ELISA). In result, OA was found to be positive in 64 (71.91%) of the 89 samples analysed, whereas OA was not found in 25 samples (28.09%).

Highlights

  • Mycotoxins produced by fungi are highly toxic and cause acute or chronic mycotoxicosis in animals consuming feeds contaminated with such compounds (Pfohl-Leszkowicz & Manderville, 2007)

  • It was found that plant-derived feedstuffs may be contaminated with mycotoxins before and after harvesting, and mycotoxins have been found in animal products and in egg, milk and dairy products from animals fed with rations containing such feedstuffs (Hussein & Brasel, 2001; Meucci et al, 2010)

  • Throughout the 59 samples of mixed feed analysed for Ochratoxin A; OA contamination was found higher than 5-19 ppb in 26 samples (44.07%), 20-40 ppb in 12 samples (20.34%) and >40 ppb (10.17%) in 6 samples

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Summary

Introduction

Mycotoxins produced by fungi are highly toxic and cause acute or chronic mycotoxicosis in animals consuming feeds contaminated with such compounds (Pfohl-Leszkowicz & Manderville, 2007). Ochratoxins are mycotoxins, which are produced by Aspergillus and Penicillium fungi and have three derivatives as A, B and C (Girgin, 2001; Milićević et al, 2010). Ochratoxin A (OA), one of the mycotoxins commonly found in feedstuffs, is eliminated from the body through urine (Li et al, 1997), feces (Madhyastha et al, 1992) and milk (Breitholz-Emanuelsson et al, 1993). It was reported that the dose of 14 μg/kg body weight OA does not show any clinical symptoms and toxicities in sheep

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