Abstract
Objectives: The study was conducted to identify the phenolic compounds and other possible bioactive compounds present in the leaf extracts of Tabernaemontana heyneana Wall.
 Methods: Phenolic acid profiling was carried out using ultra-high-performance liquid chromatography coupled with quadrupole-time-of-flight (QTOF). An internal standard syringic acid was used for quantitation of phenolic acids and naringenin for quantitation of flavonoids.
 Results: The leaf extracts analysis revealed the presence of 17 compounds consisting of 14 phenolic compounds and three terpenes. Among 17 compounds, eight were the major compounds, namely, coniferyaldehyde, resveratrol, sinapic alcohol, protocatechuic acid, 4-hydroxybenzaldehyde, chlorogenic acid, rutin, and protocatechuic aldehyde. This forms the first report on the identification of these pharmaceutically important compounds in T. heyneana.
 Conclusion: These findings offer clear evidence and scientific support for further research on the leaf extract of T. heyneana plant for its therapeutic purpose.
Highlights
Plant products have been regarded as a major part of traditional medicine on which about 80% of the people are dependent for their primary health care since long herbal medicines are used as remedies for different ailments
The leaf extracts analysis revealed the presence of 17 compounds consisting of 14 phenolic compounds and three terpenes
UHPLC detection in both positive [M+H]+ and negative [M-H]− ionization modes revealed the presence of 17 compounds of which 14 are phenolic acids and three are terpenes
Summary
Plant products have been regarded as a major part of traditional medicine on which about 80% of the people are dependent for their primary health care since long herbal medicines are used as remedies for different ailments. There is an increasing demand for plant products in drug development since they are effective, less toxic with no side effects. Plant secondary metabolites include phenolic compounds, alkaloids, tannins, saponins, carbohydrates, glycosides, flavonoids, and steroids. Phenolic compounds have been considered as good therapeutic agents possessing various biological activities. Development of an effective tool for chemical profiling of plant and estimation of chemical constituents is essential. Chromatographic techniques are efficient and economical ways to determine the bioactive principles in herbal drug formulation [1]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
