Abstract

Differential scanning calorimetry and freeze-fracture electron microscopy were applied to study the effects of LiCl and CaCl 2 on the lyotropic and thermotropic properties of dipalmitoylphosphatidylcholine and dipalmitoylphosphatidylethanolamine in disperions with excess water. Significant changes of the phase transition temperatures and phase transition enthalpies were observed. The phase diagrams of the systems dipalmitoylphosphatidylcholine/dipalmitoylphosphatidylethanolamine/H 2O/LiCl and dipalmitoylphosphatidylcholine/dipalmitoylphosphatidylethanolamine/H 2O/CaCl 2, showed that the influence of Li +- and Ca 2+-ion does not effect fundamental changes in the miscibility properties of the two amphoteric phospholipids.

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