Abstract
The spatial organization of phospholipids and sterols in cellular membranes plays an important role in membrane function and cell activities. Both experimental and simulation studies have shown that the spatial distribution of lipids and sterols can be heterogeneous with various morphologies in multi-component bilayer systems. Here we use coarse-grained Molecular Dynamics simulations to study the phase behavior of a quaternary lipid mixture. We obtain quantities such as density correlation functions and composition distribution functions, and we show how these observables can be analyzed to yield insight into the structure of complex lipid mixtures.
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