Phase and amplitude, two sides of functional connectivity.

Abstract

The dynamics of the human brain can be captured by estimating time-resolved functional network connectivity (trFNC). The most used method for estimating trFNC is sliding window Pearson correlation (SWPC). Methods based on instantaneous phase synchrony, which uses phase information for estimating trFNC are being increasingly used. These two approaches are similar under specific assumptions. Prior works have focused on which of these approaches is the best. Some works argue that SWPC can capture amplitude information and therefore we believe that instantaneous phase synchrony methods and SWPC capture different aspects of connectivity since phase synchrony methods work with the phase of the signal. Here we show that these two approaches result in different time-resolved information and therefore should be viewed as complimentary views of connectivity.