Abstract
CAT-2003, an orally active small molecule, reduces fasting and postprandial triglycerides (TG) in rat models of hypertriglyceridemia (HTG) by inhibiting SREBP activation and decreasing inhibitors of lipoprotein lipase (LPL). CAT-2003, a conjugate of niacin and eicosapentaenoic acid, is inactive in
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