Abstract

In the past few decades, significant attention has been made on the development of novel drug delivery system (NDDS)...

Highlights

  • In the past few decades, significant attention has been made on the development of novel drug delivery system (NDDS)

  • Drugs can be directly targeted to their site of action to inhibit toxic and undesired effects to other sites, further these can be used for bioavailability enhancement of the drugs, having poor bioavailability, to minimize the dose of drug administered and to increase pharmacological action of drug

  • Vesicular systems have been realized as extensively helpful carrier systems in different scientific domains

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Summary

Introduction

In the past few decades, significant attention has been made on the development of novel drug delivery system (NDDS). The NDDS should ideally fulfil two conditions: Firstly, it should deliver the drug at a rate directed by the requirement of the body, over the period of treatment, secondly; it should channel the active system to the site of action. Novel drug delivery efforts to either sustain drug activity at a predetermined rate, or by maintaining a relatively constant, effective drug level in the body with concomitant reduction of undesirable side effects. It can localize drug action by spatial positioning of controlled release systems adjacent to, or in the diseased tissue or organ; or target drug action by using carriers or chemical derivatization to deliver drug to specific target cell type [1].

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