Abstract
The greater Equisetum arvense is an herbaceous plant from the family Equisetaceae commonly found in North America, Europe and Asia. The plant has been used since ancient times in medical practice because of its pharmacological applications, and the presence of many biologically active compounds, including flavonoids, alkaloids, carbohydrate, proteins and amino acids, phytosterols, saponins and sterols. Scientific data reveals the existence of 0.6 to 0.9% flavonoids including apigenin glucoside, genkwanin glucoside, kaempferol glucoside, kaempferol sophoroside, luteolin glucoside, quercetin glucoside. It also contained caffeic acid, 5-7.7% silicic acid and alkaloids.
Highlights
Searching for antitumor agents is the most intensive segment in the development of new drugs
Description and medicinal uses of Equisetum arvense are monographed in the European Pharmacopoeia and in a national pharmacopoeia, and reported in well-established documents
To date, there are no studies on the impact of Equisetum arvense extracts on lymphocytes involved in inflammatory immune processes
Summary
Searching for antitumor agents is the most intensive segment in the development of new drugs. A number of pharmacological properties, e.g. antiinflammatory [2], antioxidant [3], Antileishmanial [4], antimicrobial [5], Anti-platelet aggregation [6], Cytotoxic and anticarcinogenic [7] have been reviewed and supported by clinical data By virtue of these properties E. arvense is widely used in alternative medicine to treat liver diseases, eases the pain of rheumatism and stimulates the healing of chilblains, benefit for cardiovascular problems, stop bleeding, heal ulcers and wounds, treat tuberculosis and kidney problems [89-10-11]. Antitumor actions of this plant have been studied in many in vitro and in vivo experiments. A few clinical trials suggested beneficial effect of E. arvanse in the management of human cancer [11-12-13-7]
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