Abstract
To prevent progression of sex hormone-responsive prostate and breast tumours, anti-androgens and anti-oestrogens are commonly used to induce androgen and oestrogen withdrawal. Zoladex is a potent luteinising hormone-releasing hormone agonist analogue, which has a selective effect on pituitary gonadotrophin release, and is highly effective at inducing regression of sex hormone-responsive prostate and breast tumours. Its depot formulation, active for at least 28 days, is convenient to administer and well tolerated and for the treatment of sex hormone-responsive tumours in men and women, Zoladex is an effective alternative to surgery.
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