Abstract
The pharmacological and toxicological properties of europium chloride have been studied. The intraperitoneal and oral LD 50′s were 550 mg./Kg. and 5.0 Gm./Kg., respectively. Feeding various levels of the chemical for 12 weeks produced no effect on growth, the hemogram, or any internal organ. Transient ocular irritation with no permanent ocular damage was observed, but abraded skin showed extensive scar formation. Permanent nodule formation resulted from intradermal injection. Progressive depression was observed on all biological systems studied, and death was the result of cardiovascular collapse coupled with respiratory paralysis. Neither atropinization nor epinephrine injections could counteract the lethal effects.
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