Abstract

BACKGROUND AND OBJECTIVES: Non-obstetric causes of pain during pregnancy are very common and can be disabling if not treated properly. The objective of this study is to discuss the pharmacological treatment of pain during pregnancy with a focus on drug classification and pregnancy use, therapy options, teratogenicity, increased fetal malformations and gestational complications associated with the use of therapy CONTENTS: During pregnancy, the body goes through several anatomical and physiological changes. These changes can precipitate pain, which in some cases can lead to disability. In addition, pregnancy may exacerbate pre-existing painful conditions. The choice to prescribe a drug to a pregnant woman is difficult. The changes in the body of a pregnant woman influence drug absorption, distribution, metabolism, and excretion, and may alter the expected response. CONCLUSION: The risks and benefits of the drug for the mother and the child should be considered, weighing the risks of not treating the disease adequately during pregnancy.

Highlights

  • During pregnancy, non-obstetric causes of pain are very common and can be disabling if not properly treated

  • The goal of this research was to discuss the pharmacological treatment of pain during pregnancy, focusing on drug classification and usage in pregnancy, therapy options, teratogenicity, increase in fetal malformations, and gestational complications associated with therapy use

  • In order to avoid the administration of drugs with potential risk and to facilitate their prescription during pregnancy, several classification systems based on animal and human data have been developed

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Summary

INTRODUCTION

Non-obstetric causes of pain are very common and can be disabling if not properly treated. Many anatomical and physiological changes take place in the body These changes can precipitate pain, which, in some cases, can lead to disability. The changes in the body of a pregnant woman influence the absorption, distribution, metabolism, and excretion of drugs, and may change the expected response. It should be considered the risks and benefits for both the mother and the child when using the drug, considering the risks of not treating properly the disease during pregnancy and lactation. The goal of this research was to discuss the pharmacological treatment of pain during pregnancy, focusing on drug classification and usage in pregnancy, therapy options, teratogenicity, increase in fetal malformations, and gestational complications associated with therapy use. The most relevant articles on the topic were selected and included in the paper

DRUG CLASSIFICATION FOR USE IN PREGNANCY
Australian Drug Evaluation Committee
Risk summary
Clinical considerations
OPIOID ANALGESICS
MUSCLE RELAXANTS
Findings
CONCLUSION
Full Text
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