Abstract

Several plants in the genus Pistacia are used in the treatment of various pathogenic and non-pathogenic disorders. Especially important are the major species belonging to this genus such as Pistacia lentiscus, Pistacia atlantica, Pistacia vera, Pistacia terebinthus, and Pistacia khinjuk, among others; these have been reported for their potential benefits both in medical and commercial purposes. In addition, members of this genus exhibit numerous ethnomedicinal uses, such as analgesic, anti-inflammatory, anticancer, antimicrobial, antihypertension, antihyperlipidemic, antiviral, and antiasthma. In light of these potential uses, the present chapter aimed to collect and summarize the literature about all of this medicinal information. Accordingly, this chapter focuses on the pharmacological uses and benefits of the genus Pistacia, especially those related to health issues.

Highlights

  • Pistacia, a genus that belongs to the family and order of Anacardiaceae and Sapindales, respectively, includes almost twenty species five of which have been classified and characterized as significant and economically important [1]

  • P. khinjuk, P. atlantica, P. terebinthus, and P. lentiscus are the foremost species of the genus Pistacia, where studies carried out by numerous researchers showed that the Pistacia vera L. as the utmost economically valuable species [3]

  • The findings from this study reported that treatment with pistachio could ameliorate renal failure and structural damage by mitigating inflammation and oxidative stress in the kidney [96]

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Summary

Introduction

A genus that belongs to the family and order of Anacardiaceae and Sapindales, respectively, includes almost twenty species five of which have been classified and characterized as significant and economically important [1]. Leaf extracts obtained from Pistacia lenticus and P. atlantica exert antioxidant effects with 14.16% and 19.3%, respectively [6]. P. lenticus, P. atlantica, P. palaestina, and P. vera, among others exhibited anticancer activity in numerous experimental studies. In this context, the crude extract of leaves and fruits of P. lenticus substantially suppressed the growth in the cell line of the growing melanoma [10], where inhibitory potential against BHK21 cell line has been identified in the seed oil of P. lenticus [11]. Are details about documented biological activities related to the members of the genus Pistacia

Antioxidant effect
Anti-microbial effect
Antiviral effect
Antiemetic effect
Anticancer effect
Cytotoxic effect
Antiparasitic effect
Antidiarrheal effect
Antispasmodic effect
2.11 Analgesic effect
2.12 Anti-osteoarthritis effect
Anti-inflammatory activity
Anti-gout effect
Anti- epileptic effect
Sedative and hypnotic activity
Effect on memory
Anti-fatigue effect
Anxiolytic effect
Wound healing
Diabetic wound healing effect
Anti-second degree burn
Anti-peptic ulcer effect
Neuroprotective effect
Hypoglycemic effect
Effect on GLUT
Lipid lowering effect
Anti-obesity effect
5.10 Antihypertensive effect
5.11 Acetyl cholinesterase
5.12 Nephroprotective effect
5.13 Hepatoprotective effect
5.14 Anti-melanogenic effect
5.15 Anti-nipple fissure effect
5.16 Anti-oral mucositis effect
5.17 Anthelmintic effect
5.18 Toxicological effect
Findings
Conclusions and future perspectives
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