Abstract
Rhododendron arboreum, an evergreen shrub native to the Himalayan region, is renowned for its vibrant red flowers and significant medicinal properties. This review explores the diverse pharmacological benefits of R. arboreum, which is integral to traditional medicine in the Himalayas. The plant contains bioactive compounds likeflavonoids, tannins, saponins, and phenolic acids, contributing to its therapeutic potential. Extensive research indicates that R. arboreum exhibits hepatoprotective, antimicrobial, anti-inflammatory, antioxidant, anti-diabetic, and anti-diarrheal properties. The hepatoprotective effects are evident from studies showing its ability to mitigate carbon tetrachloride-induced liver damage and normalize liver enzymes. Its antimicrobial efficacy, particularly against Gram-positive bacteria, is attributed to the bioactive compounds identified in the methanolic extracts of leaves and flowers. Anti-inflammatory and analgesic properties are prominent in the bark extracts, providing potential treatments for chronic inflammation and pain. Additionally, antioxidant studies reveal that R. arboreum extracts reduce oxidative stress and free radical production. Anti-diabetic activities have been demonstrated in streptozotocin-induced diabetic models, showing improved blood glucose levels and lipid profiles. The plant's anti-diarrheal efficacy is supported by animal models indicating reduced gastrointestinal motility and enhanced absorption of water and electrolytes. R. arboreum faces threats from climate change, habitat destruction, and overexploitation, necessitating effective conservation strategies. Genetic studies reveal significant diversity within the species, essential for its adaptation and long-term survival, and offer opportunities for breeding programs. Comprehensive conservation efforts, including habitat protection, sustainable use practices, and the integration of traditional knowledge with scientific research, are imperative. This review highlights the need for sustainable conservation strategies and further research to fully harness the medicinal potential of R. arboreum, ensuring its availability for future therapeutic applications.
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