Pharmacological Assessment, Green synthesis and Characterization of Silver Nanoparticles of Sonneratia apetala Buch.-Ham. Leaves

Peddinti Nagababu ,Vanga S Rao

doi:10.7324/japs.2017.70824

Abstract

The present investigation involved the screening and evaluation of S. apetala leaf crude extracts for the phytochemicals, antibacterial activity and antioxidant activity. Green synthesis of AgNPs using aqueous leaf extract, Characterization and antibacterial activity of synthesized nanoparticles were also carried out in the study. Outcome of all the experiments carried out suggests the existence of most of the phytochemicals in the leaves and are having some important biological activities. Further work is needed to isolate, purify and identify the exact active principle which is the cause for the biological activities. The Green synthesis is a simple, low cost and ecofriendly approach without any huge inputs in terms of energy. This is the first report of Green synthesis of silver nanoparticles for this plant. Being exhibiting greater antibacterial activity, phytochemical based nanoparticles may stand as a potential remedy in developing drugs against antibiotic resistant bacteria.

Highlights

There is an imperative need to explore new warfare schemes to combat against multi drug resistant bacteria and to subdue the problems of chemical drug consumption in order to control the microbial infections
Green synthesis of plant leaf mediated silver nanoparticles, its characterization and antibacterial activity were attempted as there is no earlier report on the green synthesis of S. apetala leaf AgNPs
Phytochemical screening Phytochemical screening of the leaf extracts disclosed that the solvent extracts contain almost all phytochemicals tested including alkaloids, terpenoids, flavonoids, saponins, carbohydrates, steroids, tannins and free anthraquinones (Table-1)

Summary

INTRODUCTION

There is an imperative need to explore new warfare schemes to combat against multi drug resistant bacteria and to subdue the problems of chemical drug consumption in order to control the microbial infections. These drugs from plants are less harmful, side effects are minimal and cost effective (Harishchandra et al, 2012). Mangrove plants are rich in natural antioxidants and contain bioactive compounds which are active against many pathogenic bacteria. The present study aimed to assess the qualitative nature of the phytochemical constituents and to evaluate the antibacterial and antioxidant activities of S. apetala leaf extracts. Green synthesis of plant leaf mediated silver nanoparticles, its characterization and antibacterial activity were attempted as there is no earlier report on the green synthesis of S. apetala leaf AgNPs

MATERIALS AND METHODS

RESULTS

13. Alkaloids

DISCUSSION

CONCLUSION