Abstract

In this autobiographical sketch, the author discusses the development of his interest in the biological sciences, crediting his father, his first employer, his high school science teacher, and his college pharmacognosy professor with initially shaping his career. His early work on ergot alkaloid biosynthesis and subsequently, together with students and colleagues, on the toxic constituents of basidiomycetes is detailed. This is followed by comments on his developing interest in the therapeutic utility of herbs and phytomedicinals. A concern with the beneficial use of such products stemmed largely from observations made during sabbatical leaves and frequent travel in Germany. The importance of such botanicals (not currently recognized as drugs in the United States) in our developing health-care system is emphasized. The author concludes his comments by thanking his wife, his teachers, his students, and his many colleagues and friends for their unstinting assistance and support during his entire career.

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