Pharmacognostical and Pharmaceutical Analysis of Amavatari Rasa- A Herbo-mineral Compound

Abstract

Amavatari Rasa is a herbo-mineral formulation, composed of processed mercury, sulphar, Terminalia chebula Retz, Terminalia bellerica Roxb., Phyllanthus embilica (Embelica officinalis Gaertn), Plambagozeylenica Linn., Commiphora wightii (Arn) Bhand and Ricinuscommunis Linn. This formulation is routinely practiced in cases of Rheumatoid Arthritis, but preliminary physicochemical and pharmacognostical profiles are not available. Considering this, an attempt has been made to develop this profile. Pharmacognostical study of raw drugs was carried out. Organoleptic features of fine powder made out of crude drugs were within the standard range. Loss on drying (LOD) was 0.5% w/w, total ash14.5% w/w, acid insoluble ash3.5%w/w and pH 6.5 was obtained as a result of analytical studies. High Performance Thin Layer Chromatography (HPTLC) showed difference of results when the sample scanned at two wave lengths i.e., 254 nm and 366 nm having 14 and 12 spots respectively. This shows presence of certain constituents in the powder and is helpful for the easy separation of these constituents. All above parameters helps to prepare the finger printing of classical drug Amavatari Rasa. Keywords: Amavatari Rasa, Rheumatoid Arthritis, HPTLC, Pharmacognostical study, Amalaki Cite this Article Sonam S. Bhinde, P.K. Prajapati, Galib, Harisha C.R, VJ Shukla. Pharmacognostical and Pharmaceutical Analysis of Amavatari Rasa: A Herbo-mineral Compound. Research and Reviews: A Journal of Pharmaceutical Science. 2016; 7(2): 6–10p.