PHARMACOGNOSTIC EVALUATION OF GOMPHRENA SERRATA ROOT

DSNBK Prasanth

doi:10.22270/ujpr.v2i4.r2

Abstract

Objectives: Gomphrena serrata (Amaranthaceae) has been utilized for many ailments in the conventional system ethnomedicinally; most significantly against bronchial asthma, diarrhea, hay fever, pains, tonic, carminative, diabetes, dermatitis, and piles. The key challenge experienced in the standardization of herbal drugs is the correct identification of the plant source. Thus, setting up quality control parameters by means of pharmacognostic and phytochemical analysis which assures the purity, safety, and efficiency of G. serrata is necessary. The current research was conducted to assess the pharmacognostic characteristics including macroscopic, microscopic, phytochemical and physicochemical parameters of the root of G. serrata. Methods: Micro, as well as macroscopic characteristics was investigated. Physicochemical parameters had been done by implementing WHO suggested parameters; preliminary phytochemical and fluorescent evaluation of root was executed for appropriate identification and standardization. Results: The color, shape, size, odor, and surface characteristics were reported from the root and powdered root material of G. serrata. Light microscope images of cross section and powdered root revealed the presence of lignified xylem fibers, xylem vessels, cork cells and parenchyma cells. Phytochemical testing confirmed the presence of alkaloids, carbohydrates, saponins, tannins, proteins, amino acids, phytosterols and flavonoids. Physicochemical parameters such as moisture content, ash value, extractive value and fluorescent behavior of root powder have also been established Conclusion: The current research is useful in order to supplement the information with regard to its standardization, identification and in carrying out further investigation in Ayurvedic system of medicine. Peer Review History: Received 24 July 2017; Revised 22 August; Accepted 28 August, Available online 15 September 2017 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file: Reviewer's Comments: Average Peer review marks at initial stage: 4.0/10 Average Peer review marks at publication stage: 7.5/10 Reviewer(s) detail: Dr. Marwa A. A. Fayed, University of Sadat City, Egypt, maafayed@gmail.com Dr. Mohamed Said Fathy Al-Refaey, University of Sadat City, Menofia, Egypt, Mohamed.said@fop.usc.edu.eg Similar Articles: PURIFICATION AND BIOLOGICAL ACTIVITIES OF COMBINATION OF HEMI-SYNTHESIZED THIOSEMICARBAZONES OF MITRACARPUS SCABER ZUCC

Highlights

Morphological characteristics The morphological characteristics of G. serrata root were described in Figure 1 and Table 1
Anatomical description Root The transverse section of the root of G. serrata showed the presence of Cortex was made up of thin walled parenchymatous cells with very small intercellular spaces
The prominent diagnostic characteristics of the root were xylem fibers, lignified xylem vessels, cork cells and parenchymatous cells. These characters can be utilized for standardization of drugs as well as used for preparation of plant monograph and reduces the possibilities of adulteration, when the drug is available in the powdered form studies of physicochemical parameters can serve as an important source to judge the purity and quality of crude drugs

Summary

Objectives

Gomphrena serrata (Amaranthaceae) has been utilized for many ailments in the conventional system ethnomedicinally; most significantly against bronchial asthma, diarrhea, hay fever, pains, tonic, carminative, diabetes, dermatitis, and piles. The current research was conducted to assess the pharmacognostic characteristics including macroscopic, microscopic, phytochemical and physicochemical parameters of the root of G. serrata. Physicochemical parameters had been done by implementing WHO suggested parameters; preliminary phytochemical and fluorescent evaluation of root was executed for appropriate identification and standardization. Phytochemical testing confirmed the presence of alkaloids, carbohydrates, saponins, tannins, proteins, amino acids, phytosterols and flavonoids. Physicochemical parameters such as moisture content, ash value, extractive value and fluorescent behavior of root powder have been established Conclusion: The current research is useful in order to supplement the information with regard to its standardization, identification and in carrying out further investigation in Ayurvedic system of medicine.

Methods

Results

Discussion

Conclusion