PHARMACOGNOSTIC AND ANALYTICAL STUDY OF CHANDRODAYA VARTI: AN AYURVEDIC FORMULATION

Abstract

Chandrodaya varti is a herbomineral compound indicated for ophthalmic diseases. Its ingredients consist of specific properties so that they can be used in managing Garbhasya grivagata vrana (Cervical Erosion). Chandrodaya Varti constitutes 9 ingredients, of which 6 are herbal drugs, 1 mineral, 1 sea and 1 animal origin. The pharmacognostic and analytical study revealed the specific characteristics of all active constituents used in preparation. The present work was carried out to standardize the finished product of Chandrodaya varti to confirm its identity, quality and purity. The presence of oil globules, starch grains, stone cells, macro sclereids stone cells, rhizome and prismatic crystal were the microscopic features of the powder of the prepared drug. Physiochemical analysis of Chandrodaya varti showed a loss on drying value of 8.9%, a water-soluble extractive value of 36.1%, alcohol soluble extractive of 26.9%, total ash of 10.9%, acid insoluble ash of 10.8%, pH 5.85 and the physicochemical analysis of Chandrodaya varti ash showed the loss on drying 0.01%, water-soluble extractive 34.4%, alcohol soluble extractive 9.8% and pH 13.37. HPTLC of Chandrodaya varti is the preliminary quantitative analysis which shows 11 spots at Rf value 0.11, 0.15, 0.21, 0.28, 0.31, 0.38, 0.47, 0.54, 0.62, 0.68, 0.79 in UV 254 nm and 11 spots at Rf value 0.15, 0.21, 0.31, 0.38, 0.42, 0.50, 0.54, 0.62, 0.79, 0.82, 0.89 in UV 366 nm and 7 spots at Rf value 0.15, 0.31, 0.42, 0.50, 0.54, 0.62, 0.79 in UV 540 nm.