Pharmaceutico-Analytical study of Shadbindu taila

Anup B Thakar,Harisha C R,Shukla V J,Sreekala A P

doi:10.47552/ijam.v12i3.1878

Abstract

Introduction: Shadbindu taila is an Ayurvedic herbo-mineral preparation used in a variety of clinical conditions especially in diseases of upper part of body. This taila is described as exceptionally beneficial for improving the strength of hands. Before a human trial it is essential to evaluate the quality and authenticity of the trial drug, Standardization is needed for assuring quality of any drug and it should be started with the identification and authentication of the drug Materials and method: Pharmacognostical evaluation carried out at Pharmacognosy department, ITRA, Jamnagar, pharmaceutical and HPTLC study were done at Pharmaceutical chemistry department, ITRA, Jamnagar. Microbiological evaluation was carried out at department of Microbiology I.T.R.A, Jamnagar. Results: Organoleptic examination: Colour: Greenish Brown, Odour: Aromatic, Taste: Salty, Touch: Viscous, oily. Pharmaceutical evaluation: specific gravity 0.9177, density 0.8753 Refractive Index 1 .4860, Acid Value 4.042, Saponification Value 132.43, Iodine Value 169.33 HPTLC at 254nm (short wave) showed mainly 6 major spot and at 366 nm (long wave) showed 2 major spots. No organisms isolated in aerobic and fungal culture, in microbiology evaluation. Conclusion: The trial drug is authentic and devoid of any adulteration. All quality control parameters were found to be within the permissible pharmacopeial limits and the stability and shelf life of the trial drug also will be more as per the pharmaceutical parameters.

Highlights

In a clinical trial, human trial is situated at the end of the sequence, so that the trial drug should be evaluated in every aspect, from the beginning of the collection of raw drug, processing, preparation and after the preparation
Shadbindu taila is an Ayurvedic herbo-mineral preparation used in a variety of clinical conditions especially in diseases of upper part of body
The drugs were powdered separately, and they were subjected to Sreekala A P et al, Pharmaceutico-Analytical study of Shadbindu taila pharmacognostical evaluation at Pharmacognosy laboratory, I.T.R.A., Jamnagar, Gujarat

Summary

Introduction

Shadbindu taila is an Ayurvedic herbo-mineral preparation used in a variety of clinical conditions especially in diseases of upper part of body. When the demand of herbal medicine is not fulfilled by the available resources, adulterants were added to compensate it, which means the actual drug is being replaced by another drug of different botanical identity and property. This will eventually leads to a compromise in maintaining the proper standard of formulations. Due to these reasons, Standardization is needed for assuring quality of any drug and it should be started with the identification and authentication of the drug.

Methods

Results

Conclusion