Abstract

THE PHARMACEUTICAL industry has formed an eight-member Commission on Medicine for Treating Drug Dependence and Abuse to work with government agencies in expediting promising pharmacologic approaches to the treatment of addiction. It is chaired by Harry M. Meyer, Jr, MD, president, Medical Research Division, American Cyanamid Company, Wayne, NJ. Frederick K. Goodwin, MD, administrator, Alcohol, Drug Abuse, and Mental Health Administration, Rockville, Md, points to what he calls virtual explosion of knowledge in the understanding of neurochemical mechanisms of behavior. What has been called the psychopharmacological revolution permits us to target therapeutic compounds with ever-increasing specificity, he says. We have advanced from relying on the observations of drug effects on a particular condition to a capacity to rationally design compounds that will redress the specific neurochemical deficiencies associated with illnesses such as addiction, Goodwin says. The commission's goals, as Goodwin sees them, are to discover possibly effective agents that

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