Abstract
Front Cover: Positron emission tomography (PET) imaging of hypoxia using the radiotracer [18F]FMISO suffers from a poor signal-to-noise ratio due to the unwanted uptake and slow clearance of the radiotracer in surrounding non-hypoxic cells. In article 2000061, Jason S. Lewis, Thomas P. Davis, and co-workers decrease the uptake in non-hypoxic cells by delivering the radiotracer using pH-responsive polymers, which only release the radiotracer in the acidic microenvironment of hypoxic cells. Cover design credit: Memorial Sloan Kettering Cancer Center.
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