Abstract
PET scanning for evaluation of bone metabolism
Highlights
Combined positron emission tomography (PET)/CT and PET/MRI scanners make it possible to correlate the functional data from PET with morphological images (Foldager et al 2008)
Sir–With great interest we read the paper of Ullmark et al on using positron emission tomography (PET) to assess bone metabolic activity (Ullmark et al 2009)
The principle of positron emission tomography PET scanning is based on a short-lived radioactive tracer, which decays by emitting a positron
Summary
Sir–With great interest we read the paper of Ullmark et al on using positron emission tomography (PET) to assess bone metabolic activity (Ullmark et al 2009). A large increase in availability of fluoride PET is anticipated in the coming years, as more clinically-oriented PET centers introduce fluoride PET/CT for routine scanning in benign and malignant bone diseases (Grant et al 2008) This development is good news for researchers in orthopedics, and will probably spark a range of novel approaches for noninvasive studies of bone metabolism. We are confident about the use of simplified quantification in the hip area, but would encourage future researchers engaging other parts of the skeleton to perform validating work Another important technical aspect to take into consideration when planning a study is the details related to the graphical analysis of images. This is a fact that has to be dealt with in all imaging studies to some degree, and the rationale for our use of ROIs of at least 1 cm
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