Abstract

Leslie Z. Benet is Professor and Former Chair at the University of California San Francisco (UCSF), Department of Bioengineering and Therapeutic Sciences, and Department of Pharmaceutical Chemistry. Professor Benet has had a profound impact on the development of fundamental concepts in pharmacokinetics, and the application of these principles in patient care and drug development. This theme issue is dedicated to Professor Benet in tribute to his significant contributions to the pharmaceutical sciences. An outstanding commentary that details Professor Benet’s career path and scientific achievements over the past 50 years was published recently in Pharm Res.1 We chose to provide a different perspective for the reader by focusing this commentary on those intangible factors that make Professor Benet truly a legend in the pharmaceutical sciences. In gathering information for this “C versus T” commentary, we interviewed Professor Benet and contacted scientific colleagues, professional mentees, and family. We asked each to share a brief perspective from their vantage point on this giant in the field. Many great “Les Benet” attributes emerged including energy, pas-

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