Abstract
Candida species, members of the normal body flora, are opportunistic mycosis agents that can cause infections associated with high morbidity and mortality rates in the presence of underlying predisposing factors. In recent studies, it has been reported that the incidence of invasive Candida infections caused by Candida species, such as non-albicans Candidaparapsilosis, Candida tropicalis, Candida glabrata, and Candida auris, in which antifungal drug resistance is more common, has increased, in addition to Candidaalbicans, the most frequently detected Candida species. In this context, the objective of this review article is to discuss the molecular mechanisms and biofilm-related factors responsible for the antifungal drug resistance developed in Candida species.
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