Abstract

This study sought to determine if personalized moderate-intensity continuous exercise training (MICT) combined with high-intensity interval training (HIIT) was more effective at improving comprehensive training responsiveness than MICT alone. Apparently healthy, but physically inactive men and women (n = 54) were randomized to a non-exercise control group or one of two 13-week exercise training groups: (1) a personalized MICT + HIIT aerobic and resistance training program based on the American Council on Exercise guidelines, or (2) a standardized MICT aerobic and resistance training program designed according to current American College of Sports Medicine guidelines. Mean changes in maximal oxygen uptake (VO2max) and Metabolic (MetS) z-score in the personalized MICT + HIIT group were more favorable (p < 0.05) when compared to both the standardized MICT and control groups. Additionally, on the individual level, there were positive improvements in VO2max (Δ > 4.9%) and MetS z-score (Δ ≤ −0.48) in 100% (16/16) of participants in the personalized MICT + HIIT group. In the present study, a personalized exercise prescription combining MICT + HIIT in conjunction with resistance training elicited greater improvements in VO2max, MetS z-score reductions, and diminished inter-individual variation in VO2max and cardiometabolic training responses when compared to standardized MICT.

Highlights

  • It is well established that a low cardiorespiratory fitness (CRF) level is a risk factor for coronary heart disease and cardiovascular disease (CVD) mortality [1]

  • The purpose of this study was to determine if personalized moderate-intensity continuous exercise training (MICT) combined with high-intensity interval training (HIIT) would be more effective at improving training responsiveness than MICT alone

  • HIITversus versus standardized standardized MICT, both exercise interventions combined with a resistance training component prescribed according to recommended guidelines by two world leading professional organizations in the field of exercise science (ACSM or American Council on Exercise (ACE))

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Summary

Introduction

It is well established that a low cardiorespiratory fitness (CRF) level is a risk factor for coronary heart disease and cardiovascular disease (CVD) mortality [1]. Regular aerobic exercise training following standardized guidelines has been demonstrated to be an effective tool in improving CRF [2]. There is considerable individual variability in training adaptations including the so-termed ‘non-responders’ and, in some instances, ‘adverse responders’ [3,4]. This variability in training responsiveness is not well understood and may be attributable to various factors including the absence of set definitions in the literature for responders/non-responders and a one size fits all approach to exercise prescription [5]. Public Health 2019, 16, 2088; doi:10.3390/ijerph16122088 www.mdpi.com/journal/ijerph

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