Abstract

In recent years, the parasitic protozoan Blastocystis spp., inhabiting in the human gastrointestinal tract, has begun to attract more and more attention on the site of parasitologists. A high incidence of blastocyst contamination was revealed in individuals of various population groups. In this paper, the results of the study showing high rates of invasiveness of foundry workers by the above-mentioned protozoan, characterized by hazardous working conditions of both physical and chemical nature. The ability of protozoa to inhabit a particular ecological niche depends on their biological properties; thus, persistence factors are of particular interest. The article describes the persistent potential of Blastocystis spp., inhabiting the human intestines. Persistent properties in prokaryotes is a significant physiological factor for their existence and determine the mechanism of interaction of microorganisms that form the intestinal microflora. The complex of persistence factors (ALA, ALFA, and AHA) of Blastocystis spp. was studied. A direct correlation between the persistent activity of the blastocysts and the severity of intestinal microbiocenosis disorders was found. The effect of destabilizing production factors leading to the restructuring of the intestinal biome has been established, contributing to a decrease in the indigenous group of microorganisms and an increase of opportunistic flora. The received data allow using the most important biological properties of the survival of

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