Persistence of COVID-19 Symptoms after Recovery in Mexican Population.

Carlos E Galván-Tejada,Carolina Rodríguez-Quiñones,Laura A Zanella-Calzada,Alberto Cervantes-Villagrana,Karla Herrera-García,Cintya Fabiola Herrera-García,Jocelyn L Ruiz De Avila,Mónica Martínez-Acuña,Juan Daniel De Luna Amaro,Karen E Villagrana-Bañuelos,Julio Ramírez-Barranco,Hamurabi Gamboa-Rosales,Bruno Rivas-Santiago,Fuensanta Reyes-Escobedo,Jorge I Galván-Tejada,Irma E Gonzalez-Curiel,José M Celaya-Padilla,Susana Godina-González

doi:10.3390/ijerph17249367

Abstract

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the coronavirus disease (COVID-19), a highly contagious infectious disease that has caused many deaths worldwide. Despite global efforts, it continues to cause great losses, and leaving multiple unknowns that we must resolve in order to face the pandemic more effectively. One of the questions that has arisen recently is what happens, after recovering from COVID-19. For this reason, the objective of this study is to identify the risk of presenting persistent symptoms in recovered from COVID-19. This case-control study was conducted in one state of Mexico. Initially the data were obtained from the participants, through a questionnaire about symptoms that they had at the moment of the interview. Initially were captured the collected data, to make a dataset. After the pre-processed using the R project tool to eliminate outliers or missing data. Obtained finally a total of 219 participants, 141 recovered and 78 controls. It was used confidence level of 90% and a margin of error of 7%. From results it was obtained that all symptoms have an associated risk in those recovered. The relative risk of the selected symptoms in the recovered patients goes from 3 to 22 times, being infinite for the case of dyspnea, due to the fact that there is no control that presents this symptom at the moment of the interview, followed by the nausea and the anosmia with a RR of 8.5. Therefore, public health strategies must be rethought, to treat or rehabilitate, avoiding chronic problems in patients recovered from COVID-19.

Highlights

The health emergency caused by a novel virus, designated as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is responsible for coronavirus disease (COVID-19), highly contagious infectious disease that has caused more than 38 million cases and more than a million deaths in approximately 150 countries [1]
The results of this study on persistent symptoms in patients recovered from COVID-19 coincide with regional studies from other countries, such as those carried out in Italy, Germany, the United
Referring to the presence of a post-COVID syndrome in which symptoms persist with different frequency after recovering from their initial illness

Summary

Introduction

The health emergency caused by a novel virus, designated as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is responsible for coronavirus disease (COVID-19), highly contagious infectious disease that has caused more than 38 million cases and more than a million deaths in approximately 150 countries [1]. Since February 2020 from to date, in Mexico, have been reported more than 800,000 confirmed cases and more than 84,000 deaths by this disease [2], numbers that continue increasing daily. This disease is generally characterized by a respiratory condition, the literature [3,4,5] mentions the existence of a wide range of manifestations, ranging from people asymptomatic, since to serious clinical pictures that require intensive care and others who die from this disease. The clinical criteria include; acute onset of fever plus cough. Any case that presents severe acute respiratory disease

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