Abstract
Publisher Summary The peroxisome is a ubiquitous intracellular organelle present in eukaryotes. It is classically defined as a subcellular compartment containing catalase and one H2O2-producing oxidase. Peroxisomes function in the catabolism of a wide variety of substrates, such as fatty acids, D-amino acids, L-α-hydroxy acids, uric acid, and polyamines. Several human genetic disorders with evidence of the absence of peroxisomes are linked to various biochemical dysfunctions. Peroxisomal diseases include 12 different disorders. Hence, the peroxisome plays a crucial metabolic role. This chapter discusses two topics in the study of peroxisome biogenesis: peroxisomal topogenic signals and pathogenic genes of human peroxisome-deficient disorders.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
