Permissive Hypotension in Severe Trauma

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Exsanguinating hemorrhage is a leading cause of death after severe trauma. Large volumes of fluid resuscitation are generally employed to combat hypovolemia. However, such a strategy could lead to a rise in blood pressure with clot dislodgement and continued hemorrhage. Would a limited resuscitation strategy combined with early surgical intervention improve outcomes in bleeding trauma patients? This chapter evaluates the efficacy of a controlled resuscitation strategy targeting permissive hypotension in trauma patients with ongoing hemorrhage.