Permeability of rat neurohypophysial blood vessels for neurophysins and ferritin in acute hyperoxia

Abstract

The time course of the release of vasopressin-binding (nicotine-stimulated) and oxytocin-binding (estrogen-stimulated) neurophysins (NPs) into the rat pituitary and blood serum has been studied during the convulsive phase of hyperbaric oxygenation (HBO) and the postconvulsive period (PCP). The ultrastructure of the posterior pituitary (neurohypophysis) and the state of the blood-pituitary barrier in the caudal region of the gland have been studied with the use of ferritin as an exogenous marker of vascular permeability.