Perm1 Protects the Heart From Pressure Overload-Induced Dysfunction by Promoting Oxidative Metabolism.

Abstract

HomeCirculationVol. 147, No. 11Perm1 Protects the Heart From Pressure Overload–Induced Dysfunction by Promoting Oxidative Metabolism No AccessLetterRequest AccessFull TextAboutView Full TextView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toNo AccessLetterRequest AccessFull TextPerm1 Protects the Heart From Pressure Overload–Induced Dysfunction by Promoting Oxidative Metabolism Shizuko Tachibana, PhD, Nam-Kyung Yu, PhD, Ruixia Li, MD, Carolina Fernandez-Costa, PhD, Alex Liang, BS, Janet Choi, BS, Dayoen Jung, BS, Changchun Xiao, PhD, Anastasia Kralli, PhD, John R. Yates III, PhD, Robert S. Ross, MD, MBA and Yoshitake Cho, PhD Shizuko TachibanaShizuko Tachibana Division of Cardiovascular Medicine, Department of Medicine, University of California, San Diego, La Jolla (S.T., R.L., A.L., J.C., D.J., R.S.R., Y.C.). Search for more papers by this author , Nam-Kyung YuNam-Kyung Yu Departments of Molecular Medicine and Neurobiology (N.-K.Y., C.F.-C., J.R.Y.), The Scripps Research Institute, La Jolla, CA. Search for more papers by this author , Ruixia LiRuixia Li Division of Cardiovascular Medicine, Department of Medicine, University of California, San Diego, La Jolla (S.T., R.L., A.L., J.C., D.J., R.S.R., Y.C.). Department of Medicine/Cardiology, Veterans Administration Healthcare, San Diego, CA (R.L., A.L., R.S.R., Y.C.). Search for more papers by this author , Carolina Fernandez-CostaCarolina Fernandez-Costa Departments of Molecular Medicine and Neurobiology (N.-K.Y., C.F.-C., J.R.Y.), The Scripps Research Institute, La Jolla, CA. Search for more papers by this author , Alex LiangAlex Liang Division of Cardiovascular Medicine, Department of Medicine, University of California, San Diego, La Jolla (S.T., R.L., A.L., J.C., D.J., R.S.R., Y.C.). Department of Medicine/Cardiology, Veterans Administration Healthcare, San Diego, CA (R.L., A.L., R.S.R., Y.C.). Search for more papers by this author , Janet ChoiJanet Choi Division of Cardiovascular Medicine, Department of Medicine, University of California, San Diego, La Jolla (S.T., R.L., A.L., J.C., D.J., R.S.R., Y.C.). Search for more papers by this author , Dayoen JungDayoen Jung Division of Cardiovascular Medicine, Department of Medicine, University of California, San Diego, La Jolla (S.T., R.L., A.L., J.C., D.J., R.S.R., Y.C.). Search for more papers by this author , Changchun XiaoChangchun Xiao Department of Immunology and Microbiology (C.X.), The Scripps Research Institute, La Jolla, CA. Search for more papers by this author , Anastasia KralliAnastasia Kralli Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD (A.K.). Search for more papers by this author , John R. Yates IIIJohn R. Yates III Departments of Molecular Medicine and Neurobiology (N.-K.Y., C.F.-C., J.R.Y.), The Scripps Research Institute, La Jolla, CA. Search for more papers by this author , Robert S. RossRobert S. Ross Correspondence to: Robert S. Ross, MD, MBA, Division of Cardiovascular Medicine, Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093. Email E-mail Address: [email protected] https://orcid.org/0000-0003-2195-8982 Division of Cardiovascular Medicine, Department of Medicine, University of California, San Diego, La Jolla (S.T., R.L., A.L., J.C., D.J., R.S.R., Y.C.). Department of Medicine/Cardiology, Veterans Administration Healthcare, San Diego, CA (R.L., A.L., R.S.R., Y.C.). Search for more papers by this author and Yoshitake ChoYoshitake Cho Correspondence to: Yoshitake Cho, PhD, Division of Cardiovascular Medicine, Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093. Email E-mail Address: [email protected] https://orcid.org/0000-0002-7161-3248 Division of Cardiovascular Medicine, Department of Medicine, University of California, San Diego, La Jolla (S.T., R.L., A.L., J.C., D.J., R.S.R., Y.C.). Department of Medicine/Cardiology, Veterans Administration Healthcare, San Diego, CA (R.L., A.L., R.S.R., Y.C.). Search for more papers by this author Originally published13 Mar 2023https://doi.org/10.1161/CIRCULATIONAHA.122.060173Circulation. 2023;147:916–919FootnotesCirculation is available at www.ahajournals.org/journal/circFor Sources of Funding and Disclosures, see page 919.Correspondence to: Yoshitake Cho, PhD, Division of Cardiovascular Medicine, Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093. Email [email protected]ucsd.eduCorrespondence to: Robert S. Ross, MD, MBA, Division of Cardiovascular Medicine, Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093. Email [email protected]ucsd.edu