Abstract
Systemic sclerosis is an immune-mediated connective tissue disease characterized by fibrosis of the skin and internal organs. Although systemic sclerosis is uncommon, it has high morbidity and mortality and associated with various complications such as scleroderma renal crisis, pulmonary arterial hypertension and lung fibrosis. Understanding the pathogenesis of systemic sclerosis is essential to allow better management of the disease. Scleroderma renal crisis (SRC) is a serious complication and up to 50% of the patients will progress to End-Stage Renal Disease (ESRD) requiring renal replacement therapy (RRT). Peritoneal dialysis has emerged as an effective modality to treat this condition. Here, we report a unique case of a 34-year-old female who developed ESRD secondary to SRC and remained on peritoneal dialysis for five years with excellent outcomes.
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