Abstract
Percutaneous coronary intervention can be associated with several complications such as periprocedural myocardial infarction (PPMI) that was defined as an elevation of CK-MB >3 times the upper limit of the normal range in at least two blood samples with a normal range of baseline value, prolonged ischemia as demonstrated by persistent chest pain (>20 min), or new pathological Q waves seen on the electrocardiogram. By epidemiology, periprocedural myocardial infarction was happen in about 6 – 7% patient underwent PCI and associated with adverse outcome. Therefore it is important to identify the possible factors to detect, prevent and manage this event.
Highlights
Percutaneous coronary intervention (PCI) is one of the most frequent procedures directed in a patient with the coronary syndrome
Percutaneous coronary intervention (PCI) is linked to a number of complications, including periprocedural myocardial infarction (PPMI), which is defined as an increase in creatine kinase-MB (CK-MB) levels of >3 times the upper limit of the normal range in at least two blood samples with a normal baseline value, prolonged ischemia as evidenced by persistent chest pain, and new pathological Q waves on the electrocardiogram (ECG)
In a randomized study including 150 patients receiving PCI, Laskey et al discovered that ischemia preconditioning produced during PCI reduced postprocedural creatine kinase (CK) increase by 70% when compared to multiple inflations without intervening reperfusion intervals or single balloon inflation >60 seconds.[18]
Summary
Percutaneous coronary intervention (PCI) is one of the most frequent procedures directed in a patient with the coronary syndrome. Periprocedural myocardial infarction is a notable entanglement of PCI procedures and is habitually seen in a significant extent of patients who went through PCI procedures.[1,2] A few factors were recognized identified with the periprocedural myocardial ischemia. This article review talked about the plausible mechanism, diagnostic, and management of periprocedural myocardial infarction
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