Abstract
As peripheral vascular disease affects more and more people in the world, interventional treatment of peripheral blood vessels evolves from percutaneous transluminal angioplasty to bioresorbable vascular scaffolds (BVS). At present, the materials of peripheral vascular bioresorbable scaffolds mainly include polymers and metal materials, and have achieved certain clinical application effects. Examples of these BVS are provided, and their advantages and defects are discussed. Poly-L-lactic acid is most commonly used in polymer BVS. There have been some polymer BVS entering clinical research for peripheral blood vessels since the 10 s, and have various outcomes. Metal materials for BVS mainly include magnesium alloy, iron alloy, and zinc alloy. The improved magnesium alloy BVS show excellent antiplatelet adhesion ability and can reduce the formation of acute stent thrombosis in clinical research. The iron alloy BVS and zinc alloy BVS also show excellent performance in animal experiments. The drug coating of BVS is expected to be improved. Finally, prospects of future development are highlighted. With the continuous improvement of manufacturing and drug-coating process, their therapeutic effect is expected to continue to improve.
Published Version
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