Abstract
Primary sensory nerves do not only transfer messages to the central nervous system but also transmit messages to the periphery. The peripheral response is one of defense, including neurogenic inflammation such as miosis and a breakdown of the blood aqueous barrier in the eye or vasodilatation and plasma extravasation in the skin. Recent pharmacological, biochemical and immuno-histochemical studies have revealed that tachykinins are the most likely transmitters at peripheral as well as central endings of primary sensory nerves. Furthermore, studies with trigeminal nerve-innervated and isolated rabbit iris sphincter muscle have clearly shown that the peripheral neurotransmission is affected by many neuromodulators and irritants. It is not unlikely that the neurotransmission mechanisms at peripheral endings are analogous to those at central endings in the primary sensory nerves.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
