Perioperative monitoring characteristics of infants with severe Pierre Robin syndrome

Abstract

Objective To study perioperative monitoring characteristics of severe Pierre Robin syndrome in children. Methods The clinical data of 48 infants with Pierre Robin syndrome admitted to the department of surgical intensive care unit from March 2013 to January 2015 were retrospectively reviewed. Results All 48 cases were cured and discharged without death.The average duration of mechanical ventilation after the operation was(2.76±3.58)days.There were significant differences in blood gas analysis before and after treatment in surgical intensive care unit(pH: 7.33±0.07 vs. 7.44±0.08, PaCO2: (49.12±15.63)mmHg vs.(36.19±8.13) mmHg, PaO2: (74.28±17.09) vs.(114.00±53.55) mmHg)(P<0.05, respectively). The levels of prealbumin and retinol binding protein increased significantly after treatment[prealbumin: (0.10±0.04)g/L vs.(0.14±0.05) g/L, retinol binding protein: (19.85±9.76)mg/L vs.(25.15±8.72)m g/L](P<0.05, respectively). Conclusion Reasonable mechanical ventilation combined with available nourishments support could help to improve the prognosis of severe Pierre Robin syndrome. Key words: Pierre-Robin syndrome; Perioprative; Respirary; Nutrition