Abstract
Cardiovascular diseases, chronic obstructive pulmonary diseases, diabetes, rheumatoid arthritis, and cancer are the most common noncommunicable diseases (NCDs). These NCDs share risk factors with periodontal disease (PD), a preventable risk factor linked to lifestyle. The discussion regarding the association between these chronic diseases is more complex. There is still a significant knowledge gap particularly of the causal relationship between PD and NCDs. In this paper, we present fundamental knowledge of the mechanisms and roles of putative periodontal bacteria to gather several hypotheses, evidence that clinical studies thus far have not produced. Although the causal hypotheses are not yet clearly established on a biological basis, prevention and prophylactic measures are recommended to prevent even the possibility of such potential risk factors.
Highlights
The Sixtieth World Health Assembly (WHA60.17) highlighted in 2007 the link between oral health, general health and the quality of life
The processes that are suggested to associate periodontal diseases and chronic obstructive pulmonary disease (COPD) include the overspill of topically generated inflammatory mediators into the systemic circulation or bacteremia of oral or pulmonary origin that accelerates acute response, mechanical aspiration of oral content in the tree respiratory, and reactive oxygen species and cytokines released by systemic neutrophils at distant sites [85]
This paper alone cannot answer the question of the causal link between periodontal bacteria and the main noncommunicable diseases that are CVD, diabetes, rheumatoid arthritis (RA), cancer, and COPD
Summary
The Sixtieth World Health Assembly (WHA60.17) highlighted in 2007 the link between oral health, general health and the quality of life It explained that the prevention and treatment of chronic diseases requires the establishment of prevention programs for oral disease and oral health promotion [1]. Cardiovascular diseases, chronic obstructive pulmonary diseases, rheumatoid arthritis, diabetes, and cancer are the most common noncommunicable diseases (NCDs). These NCDs and periodontal disease (PD) have identical but preventable risk factors linked to lifestyle [5]. Oral diseases are a risk factor for general pathologies Fundamental knowledge of the mechanisms and roles of putative periodontal bacteria on the potential development of the five main noncommunicable diseases—cancer, cardiovascular diseases, diabetes, pulmonary diseases, rheumatoid arthritis—are presented
Sign-in/Register to view highlights & summary 
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call