Abstract
BackgroundMetabolic syndrome (MetS) is a pathophysiological change based on the abnormal metabolism of many substances. The study aims to investigate the performance of visceral adiposity index (VAI) and lipid accumulation product (LAP) of MetS in young adults.Methods448 young adults aged between 19 and 24 years old in Qinhuangdao had been included in this cross-sectional study. Receiver operating characteristic (ROC) curve analyses were used to assess the accuracy of these two obesity indicators for MetS.ResultsThe prevalence of MetS was 2.0%. In male subjects, LAP had the highest area under the ROC curve (AUC) value (AUC = 0.963), followed by VAI (AUC = 0.937). In female subjects, LAP also had the highest AUC value (AUC = 0.931), followed by VAI (AUC = 0.861). No significant difference was found between the two obesity indicators (P > 0.05).ConclusionThe two obesity indicators were valuable for the screening of MetS in young adults, and LAP was the simpler of the two.
Highlights
Metabolic syndrome (MetS) is a pathophysiological change based on the abnormal metabolism of many substances
lipid accumulation product (LAP) had the highest area under the Receiver operating characteristic (ROC) curve (AUC) value (AUC = 0.963), followed by visceral adiposity index (VAI) (AUC = 0.937)
The two obesity indicators were valuable for the screening of MetS in young adults, and LAP was the simpler of the two
Summary
Metabolic syndrome (MetS) is a pathophysiological change based on the abnormal metabolism of many substances. The early intervention of MetS is important for reducing the risk of developing related diseases. The VAI and LAP are two novel indexes for MetS. VAI and LAP are associated with many chronic diseases. VAI was negatively correlated with insulin sensitivity [1], and was identified as a powerful indicator of prediabetes or diabetes [2]. It was positively correlated with the risk of hyperuricemia and nonalcoholic fatty liver disease [3, 4]. The study aims to investigate the performance of visceral adiposity index (VAI) and lipid accumulation product (LAP) of MetS in young adults
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