Performance evaluation of PL-11 platelet analyzer

Abstract

Objective To evaluate and report the performance of PL-11 platelet analyzer. Methods Intravenous blood samples anticoagulated with EDTA-K2 and sodium citrate were tested by the PL-11 platelet analyzer to evaluate the intra-assay and inter-assay coefficient of variation (CV), carry-over rate, accuracy, linearity of the PL-11 platelet analyzer.Platelet aggregation rate of sodium citrate-anticoagulated fasting venous blood collected from 30 physical examinees in outpatient department of The First Affiliated Hospital of Soochow University between February and July, 2012 was detected by the PL-11 platelet analyzer and MPG-3E multifunctional double channel blood coagulation analyzer, respectively.The correlation was detected between the PL-11 platelet analyzer and MPG-3E multifunctional double channel blood coagulation analyzer. Results All the parameters were conformed to the standard of Clinical Laboratory Improvement Amendment 88.Both of the intra-assay and inter-assay CV values were less than 5%; carry-over rate was less than 1%; the accuracy and the linearity was excellent correlated to the result of photoelectric turbidimetry (R2=0.9439). Conclusions PL-11 platelet analyzer can directly use whole blood dynamics to analyze platelet aggregation process and quantitatively analyze the various components of blood cells (including platelets and red blood cells),the result reports are accurate and reliable.（Chin J Lab Med，2012,35：1139-1141） Key words: Platelet aggregation; Platelet function tests; Diagnostic equipment; Evaluation studies