Performance Evaluation of Deep Learning Architectures for Blood Pressure Estimation Using Photoplethysmography

Abstract

High blood pressure (BP) monitoring Blood pressure (BP) is one of the common cardiovascular diseases and therefore the early high blood pressure (hypertension) detection, management, and prevention are mandatory. One promising method of continuous, non-invasive blood pressure estimation is photoplethysmography (PPG). In this study, a novel method was proposed to introduce the AlexNet framework into the time-frequency domain for classification of BP levels based on PPG signals. The study was conducted using the publicly available Figshare dataset which offers PPG signals, and the blood pressure labels against them. Data balancing techniques were used to alleviate class imbalances. Preprocessing and Feature Extraction of PPG Signals. The PPG signals were preprocessed with noise filtering and signals were then transformed from 1D-time to image to facilitate robust feature extraction. The proposed classification model, based on AlexNet showed the best result, with 98.89% accuracy, recall, and precision, and 99.44% specificity. This model outperformed alternative models (VGG16, DenseNet, ResNet50, GoogleNet) for classifying BP levels into the JNC 7 report standard categories normotension, prehypertension and hypertension. This study has two primary contributions. Initially, it demonstrates the efficacy of AlexNet model to extract meaningful features from PPG signals by its hierarchical convolutional and max-pooling layers thereby enabling accurate classification of BP levels. This study underscores the potential of deep learning and PPG signals for developing a highly accurate and truly non-invasive BP monitoring system. In the second aspect, the study offers a systematic assessment and comparison of the proposed over other well-known deep-learning networks, presenting the effectiveness of the AlexNet-based one. These results are of critical importance in the development of novel non-invasive BP monitoring modalities and optimization of cardiovascular health managements and personalized health cares.