Abstract

Introduction: The manipulated medicinal product is a masterly preparation individualized to a patient from a prescription. Objective: To evaluate prescriptions at a compounding pharmacy of a federal public university in Rio de Janeiro, and to evaluate compliance with these prescriptions, in relation to the current technical-sanitary criteria. Method: This is a descriptive cross-sectional study, which evaluated 400 prescriptions in May 2015. Results: About 162 (40,00%) prescriptions presented errors, of which 132 showed exclusively bookkeeping errors, 20 exclusively, pharmacotechnical errors, and 10 both errors. Among the errors in bookkeeping, the most frequent were absence of date of issue (29%) and posology (13,00%). Among the pharmacotechnical errors, 66.33% were of incompatibility between the active and formulation, 13.33% were incompatibilities between different active in the same formulation and 23.33% were incompatibilities of the active with the semi-solid vehicle. Therefore, it was possible to identify that the prescriptions analyzed did not adequately comply with the Brazilian legislation, as errors were verified in both bookkeeping and pharmacotechnical aspects. Conclusions: Because they are manipulated drugs, which must be developed through a prescription, it is essential to carefully evaluate them to minimize or avoid damages to users.

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